What is the mechanism MEDIATOR BETWEEN THE EFFECTS OF EXERCISE AND BONE?

One of the most important factors related to structural characteristics. The functional demand imposed on the bone is a major determinant in the structural characteristics of this. The intensity of the applied stress on the bone segment affects its geometry, its microarchitecture and composition of the matrix. Definitely the intensity of the burden for the recently described effects is important and not the duration of effort, a minimum strain (a strain is equal to one unit of strength by amending the arquitctura moments bone) is required to produce an effect on bone. It has developed a theory which translate mecanoestatos impact force signals that allow an imbalance between osteoblast activity (which builds bone) and osteoclasts (bone absorbing). It is not clear if that signal increases or decreases osteoblastic activity osteoclastic or both. The strain imposed on the active bone osteocyte initiating an increase in the production of prostacyclin and the osteoblast produces prostacyclin and prostaglandin E2, minutes later it has been shown that the osteocyte is an increase of glucose 6 phosphate dehydrogenase and 24 hours later an increase in mRNA for growth factors.

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